你的这句有点怪啊，可以该成：
Enjoying your life and understanding the true meaning of life, and the most important thing is happiness
而that is 的表达应该是:
that is（to say）也就是说，意思是”即”
例如：
He will come on National Day, that is （to say）, October 1st. 他国庆节，即十月一日来．
Enjoying your life and understanding the true meaning of life, and the most important thing is happiness .
Enjoying your life and understanding the true meaning of life, that is(that is（to say）也就是说，意思是”即”), the most important thing is happiness
……that is the most important thing,it is happiness
去掉things的s
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